Journal article

Organisation of the musculature of the rat stomach

MR Di Natale, L Patten, JC Molero, MJ Stebbing, B Hunne, X Wang, Z Liu, JB Furness

Journal of Anatomy | Published : 2022

Abstract

The strengths, directions and coupling of the movements of the stomach depend on the organisation of its musculature. Although the rat has been used as a model species to study gastric function, there is no detailed, quantitative study of the arrangement of the gastric muscles in rat. Here we provide a descriptive and quantitative account, and compare it with human gastric anatomy. The rat stomach has three components of the muscularis externa, a longitudinal coat, a circular coat and an internal oblique (sling) muscle in the region of the gastro–oesophageal junction. These layers are similar to human. Unlike human, the rat stomach is also equipped with paired muscular oesophago-pyloric liga..

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University of Melbourne Researchers

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Awarded by National Institutes of Health


Funding Acknowledgements

This work was supported by NIH (SPARC) grant, The Virtual Stomach (OT2OD030538), Principal Investigators Leo Cheng (University of Auckland) and ZL (University of Michigan) and NIH (SPARC) grant ID #OT2OD023847 (Principal Investigator Terry Powley, Pudue University).